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- $Unique_ID{BRK03764}
- $Pretitle{}
- $Title{Gastritis, Giant Hypertrophic}
- $Subject{Gastritis, Giant Hypertrophic Menetrier Disease Protein-losing
- Gastroenteropathy Giant Hypertrophy of the Gastric Mucosa Hypertrophic
- Gastropathy}
- $Volume{}
- $Log{}
-
- Copyright (C) 1986 National Organization for Rare Disorders, Inc.
-
- 119:
- Gastritis, Giant Hypertrophic
-
- ** IMPORTANT **
- It is possible that the main title of the article (Giant Hypertrophic
- Gastritis) is not the name you expected. Please check the SYNONYM listing to
- find alternate names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Menetrier Disease
- Protein-losing Gastroenteropathy
- Giant Hypertrophy of the Gastric Mucosa
- Hypertrophic Gastropathy
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section.
-
-
- Giant Hypertrophic Gastritis is a rare disorder characterized by large,
- coiled ridges or folds with surface nodulation of the inner wall of the
- stomach; they often resemble polyps. These folds may affect only part of the
- stomach or they may be present throughout the entire stomach.
-
- Symptoms
-
- Characteristics of Giant Hypertrophic Gastritis may include pain, discomfort
- and tenderness in the upper middle region of the abdomen, anorexia, nausea,
- vomiting, and diarrhea. Approximately forty percent of patients vomit blood.
- Occasionally, there is an ulcer-like pain occurring after a meal and there
- may be loss of weight.
-
- If protein escapes into the stomach cavity, hypoproteinemia accompanied
- by the accumulation of excess fluid (edema) may be the result.
- Hypoproteinemia is a decrease in the amount of protein in the blood.
-
- As there may be an increased risk of gastric carcinoma in patients with
- this condition, it is important for them to be examined by a physician
- periodically.
-
- Causes
-
- The precise cause of Giant Hypertrophic Gastritis is unknown. It may be
- related to multiple endocrine adenomatosis (numerous endocrine tumors).
-
- Therapies: Standard
-
- Treatment for patients with Giant Hypertrophic Gastritis may require a high
- protein diet to correct hypoproteinemia, and, rarely, gastric resection may
- be necessary. The loss of serum protein into the stomach also may be reduced
- by the use of anticholinergic drugs.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through
- December 1988. Since NORD's resources are limited, it is not possible to
- keep every entry in the Rare Disease Database completely current and
- accurate. Please check with the agencies listed in the Resources section for
- the most current information about this disorder.
-
- Resources
-
- For more information on Giant Hypertrophic Gastritis, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- National Digestive Diseases Information Clearinghouse
- Box NDIC
- Bethesda, MD 20892
- (301) 468-2162
-
- References
-
- CECIL TEXTBOOK OF MEDICINE, 18th ed.: James B. Wyngaarden, and Lloyd H.
- Smith, Jr., Eds.: W. B. Saunders Co., 1988. Pp. 691-2.
-
-